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With that in mind, if you do decide to try not just GLP-1 supplements but any supplement, it's best to consult a health care professional first, Reierson says, "especially when it comes to those claiming to offer significant health benefits." If you buy something through a link in this article, we may earn commission.

The phase 2 trial showed that at 48 weeks, 92% of people taking 4mg lost at least 5% of their body weight

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Treatment starts at 0.25 mg weekly for four weeks to improve tolerability, then typically increases to 0.5 mg, with further escalation to 1 mg or 2 mg if needed