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Yang Tang, [email protected] These authors have contributed equally to this work and shared first authorship This article was submitted to Thyroid Endocrinology, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Without such a system, the absorption of supplemental B12 can be inconsistent and inadequate, particularly in individuals with compromised GI function or those with conditions that impair the production of IF