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Patients who were prescribed semaglutide or liraglutide for at least one year were slightly more likely to maintain or continue to lose weight in the year following treatment

The rationale for combining them is mechanistic complementarity (different signaling pathways, both implicated in tissue repair) and clinical anecdote in the peptide-therapy community not formal head-to-head or combination-vs-monotherapy data

they do not constitute approved clinical guidance, and the precise dosing schedule for any future licensed product may differ substantially depending on the formulation and delivery device authorised by regulators

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