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As molecular interactions lie at the core of most biological processes, elucidating the network of interactions between molecules is not only crucial for analyzing protein abundance and localization, PPIs, and interactions between proteins and DNA/RNA but also enhances our understanding of cell growth, differentiation, and apoptosis processes [1]

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4D clearly demonstrate an AKT1 and phospho-AKT1 increase in lipedema tissues highlighting this enzyme as a new possible biomarker for this pathology to translate to the clinical management of patients affected by this disease