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It does not require hepatic conversion

The article on how long compounded semaglutide lasts in the fridge discusses stability timelines in detail, and the question of does compounded semaglutide need to be refrigerated has a definitive answer: yes, always

Increasing BMI has been correlated with higher mortality risks, including a 29% rise in overall mortality and over a 200% increase in diabetes-related mortality for every 5-unit BMI increase above 25 kg/m (4)