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This modification uniquely induces structural rearrangements associated with amyloidogenic conversion, in contrast to other post-translational modifications on Cys10, such as, S-cysteinylation or S-glutathionylation, that do not significantly alter the native fold [22]

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The primary adverse effect is gastrointestinal discomfort, including bloating, flatulence, and diarrhoea, particularly at higher doses

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