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Furthermore, few clinical trials have demonstrated that either inhibiting mTORC1 by rapamycin (sirolimus) (60) or supplementing N-acetylcysteine (NAC), a glutathione precursor and an antioxidant (58), is therapeutically effective and improved systemic inflammation in patients with SLE

2.1.1.3 Effects of BF on liver fibrosis Clinically, liver fibrosis will gradually develop into liver cirrhosis, and it is likely to cause liver dysfunction and liver failure

doi: 10.1016/j.carbpol.2025.124141

It is believed to be due to autoimmune induced damage to the thyroid causing excess hormone release, and for this reason is not responsive to antithyroid drugs, KI or KCLO 4 , but does, if treatment is necessary, respond to prednisone(67)