Consumer evaluation context: Before purchasing any supplement positioned around GLP-1 terminology, consumers benefit from understanding the distinction between ingredient-level research and product-level evidence, recognizing that dietary supplements and prescription medications represent different categories, and maintaining realistic expectations aligned with available research
ORIGIN Trial Investigators, Gerstein HC, Bosch J, Dagenais GR, Daz R, Jung H, Maggioni AP, Pogue J, Probstfield J, Ramachandran A, Riddle MC, Rydn LE, Yusuf S
Clinical references to muscle loss during GLP-1 treatment are based on published semaglutide and tirzepatide trial data
Statements Data availability statement The datasets presented in this article are not readily available because we did not include this as part of the consent form