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This development has led to the introduction of several GLP-1 receptor agonists and DPP-4 inhibitors on the market [3], which are featured prominently in current recommendations because of their effectiveness, safety and proven cardiovascular benefits [33]
Recent RCTs are beginning to explore the dual impact of metabolic and inflammatory modulation in PsD, although no results have yet been published, representing important future perspectives in this field
15b Preventive treatments include beta-blockers, antiepileptics, calcium channel blockers, antidepressants, and CGRP antagonists
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289 At the same time, the promotion of CD8 + T cell activation and recruitment and significant inhibition of MDSCs generation and recruitment were observed in models treated with L-DON and JHU-083
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