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Independent groups have characterised the compound across overlapping research model systems, providing cross-laboratory replication for the core observations documented in the foundational papers

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Clinical trials at doses up to 40mg daily for 12 weeks have reported no serious adverse effects (Brendler & Williamson, 2019, Phytomedicine )

We continue to believe that payer-specific negotiated charges that hospitals negotiate with MA organizations capture the relative resources used to provide services to patients in order to maximize profits (or, in the case of not-for-profit hospitals, net income), subject to market ( constraints and conditions (supply and demand, community benefit requirements, etc.)