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It is noteworthy that such delivery challenges are not unique to SFN but represent a common hurdle for many bioactive phytochemicals, as comprehensively documented in the case of curcumin where nano-formulations have successfully addressed similar bioavailability limitations

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However, cancer cells can escape cellular ferroptosis by activating or remodeling various signaling pathways, including oxidative stress pathways, thereby limiting the efficacy of ferroptosis-activating targeted therapy

Map-based cloning of the pear gene MYB114 identifies an interaction with other transcription factors to coordinately regulate fruit anthocyanin biosynthesis