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Of importance, the treatment with JHU-083 resulted in the suppression of oxidative phosphorylation (OXPHOS) and glycolysis in tumor cells but upregulated oxidative metabolism in T cells, suggesting a difference in their metabolic response to Gln blockage [92]

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Expanding therapeutic indications beyond diabetes into obesity treatment multiplies the addressable market size

At a follow up appointment 3 weeks after discontinuing semaglutide, the patient had not experienced any new lesions and old lesions were in the process of healing