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Models based on mice, rats, rabbits, goats, and dogs with experimentally induced IVD degeneration have often been used [20], but these animals, with the exception of dogs, do not spontaneously develop IVD degeneration and disease

Inject too shallow and the peptide sits in the dermis

After each blood sample was taken, the catheter was flushed with heparinized lactated Ringer's solution and a volume of heparinized lactated Ringer's equal to the volume of blood taken was injected (to maintain total blood volume)

Wang Y, Huang S, Sah VP, Ross J, Brown JH, Han J, Chien KR: Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family