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Adolescent female rats treated with (THC) for 11 days and left until adulthood presented significant "behavioral despair' (forced swim test) paralleled by anhedonia (sucrose preference)

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Your own exposure & equity curve will give you less of a comprehensive read into how the thematic trend is performing and you may lose out in the long term from benefits that are secondary and tertiary to the thematic rather than just primary

Increased Fertility: Weight loss and improved hormone balance may increase fertility in females