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Your brain consumes more energy than any other organ, burning either glucose or ketones

For example, butyrate may indirectly regulate -hydroxybutyrylation by enhancing hepatic ketogenesis, generating -hydroxybutyrate as a critical substrate

However, it is widely accepted that HO-1 is a heat shock protein that is controlled by inflammatory or pro-oxidant states and is induced in various pathologies in response to oxidative stress [1]