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For example, a psychoeducational group program delivered via videoconferencing showed no general effect one year after surgery but significantly improved outcomes in patients with severe depressive symptoms [106]

Using several hormones in low doses and incorporating lifestyle interventions might maximize the clinical effect while minimizing the side effects. Clearly, many patients would find daily injections of hormones preferable to undergoing bariatric surgery, even if these injections would need to be continued in the long-term to keep the weight off

And obesity is clearly a very serious metabolic disease