Beetroot extract may have an additive effect when combined with blood pressure-lowering drugs, including: ACE inhibitors (e.g., ramipril, lisinopril) Angiotensin receptor blockers (ARBs) (e.g., losartan, candesartan) Beta-blockers (e.g., bisoprolol, atenolol) Calcium channel blockers (e.g., amlodipine, diltiazem) Diuretics (e.g., bendroflumethiazide, furosemide) This combination may result in excessive hypotension, causing dizziness, syncope, or fallsparticularly concerning in elderly patients
L-theanine supports relaxation and mood by increasing alpha-wave activity, and levels of serotonin, dopamine, and GABA in the brain.* L-theanine also has been shown to block binding of L-glutamic acid to excitatory glutamate receptors in the brain.* Glutamate receptor subtypes have been shown to modulate excitability associated with anxiety, while in depression, a hyperfunctioning glutaminergic system also may be an issue.* Continuous administration of L-theanine has been shown to increase expression of brain-derived neurotrophic factor (BDNF) protein, a protein which plays a role in neural plasticity and neurogenesis.* *These statements have not been evaluated by the Food and Drug Administration
MEET DR
CYP3A4 and CYP3A5: The Primary Enzymes Dutasteride undergoes extensive hepatic metabolism through the cytochrome P450 system, specifically CYP3A4 and CYP3A5
