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It can be prescribed as an injection or taken orally

While pooled data from the SURPASS clinical trial programme indicate that tirzepatide does not increase the risk of major cardiovascular events [61], definitive conclusions regarding its cardiovascular profile should await the results of SURPASS-CVOT, with its completion anticipated in late 2024 [60]

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Following glucose uptake the primary fate is incorporation into glycogen even though, as in the case of exercise- or contraction-mediated effects, there is an increase in its oxidation