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While NICE guidelines are considered a high-quality source of evidence, they are not the sole determinant of treatment decisions

Satiety signaling: It sends satiety signals to your hypothalamus, which reduces hunger and gives you a feeling of fullness

Patients with Renal Impairment A single-dose, open-label trial was conducted to evaluate the pharmacokinetics of saxagliptin (10 mg dose) in subjects with varying degrees of chronic renal impairment compared to subjects with normal renal function