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In addition, marked fluctuations in leptin and other hormonal secretion patterns throughout the different endocrine states during the female lifespan (Including puberty, pregnancy, and menopause) have been linked with changes in the regulation of the innate and adaptive immune systems, and disbalance between pro and anti-inflammatory states, which altogether increase the risk of developing autoimmune diseases (22, 24)

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What I've observed in my salon is that clients who follow this protocol consistently for at least 3-6 months often notice less new gray growth, improved hair quality, and in some cases, partial repigmentation of grays that have recently appeared

307 The interaction between hepcidin and FPN is also an important mechanism for iron homeostasis