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As DrugPatentWatch has noted, PEGylated liposomes achieve extended circulation through steric stabilization, and the PEG density and chain length are themselves patentable

doi:10.1038/clpt.2010.184 Lyssenko V, Lupi R, Marchetti P et al (2007) Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

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Supplementing with D3 can improve serotonin levels, potentially alleviating mood swings or feelings of depression