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Other implicated genes are Clusterin (CLU) , Sortilin-related receptor-1 (SORL1) , ATP-binding cassette subfamily A member 7 (ABCA7) , Bridging integrator 1 (BIN1) , phosphatidylinositol binding clathrin assembly protein (PICALM) , CD2 associated protein (CD2AP) , Complement component (3b/4b) receptor 1 (CR1) , CD33, triggering receptor expressed on myeloid cells 2 (TREM2) , and phospholipase D3 (PLD3) (Karch and Goate, 2015)

They can determine whether this side effect is attributed to semaglutide or something else

Many plans consider it medically necessary for weight management

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